GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.

GPR143 Polyclonal Antibody detects endogenous levels of GPR143 protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.

GPR143 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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