RACGAP1 encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. Rac GTPase activating protein 1 binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. Rac GTPase activating protein 1 plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for RACGAP1. There is a pseudogene for RACGAP1 on chromosome 12.

Rac GAP1 Polyclonal Antibody detects endogenous levels of Rac GAP1 protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:40000. Not yet tested in other applications.

Rac GAP1 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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