RAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.

Rab 3 GAP p130 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p130 protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.

Rab 3 GAP p130 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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