RPS6KB1 encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. Ribosomal protein S6 kinase B1 responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of RPS6KB1 has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for RPS6KB1 on chromosome 17.

p70 S6 kinase α Polyclonal Antibody detects endogenous levels of p70 S6 kinase α protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:40000. Not yet tested in other applications.

p70 S6 kinase α Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/p70-s6-kinase-α-polyclonal-antibody-abp52133.