OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein. Opioid binding protein/cell adhesion molecule like is localized in the plasma membrane and may have an accessory role in opioid receptor function. OPCML has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the opioid binding protein/cell adhesion molecule like is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

OBCAM Polyclonal Antibody detects endogenous levels of OBCAM protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.

OBCAM Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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