SIN3B (SIN3 Transcription Regulator Family Member B) is a Protein Coding gene.Paired amphipathic helix protein Sin3b acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.Among its related pathways are Gene Expression and Metabolism. GO annotations related to this gene include chromatin binding and RNA polymerase II transcription corepressor activity. An important paralog of this gene is SIN3A.

Sin3B Polyclonal Antibody detects endogenous levels of Sin3B protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.

Sin3B Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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