Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Inward rectifier potassium channel 2 encoded by KCNJ2 is an integral membrane protein and inward-rectifier type potassium channel. Inward rectifier potassium channel 2, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

KIR2.1 Polyclonal Antibody detects endogenous levels of KIR2.1 protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.

KIR2.1 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/kir2.1-polyclonal-antibody-abp51676.