NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. NFKB inhibitor alpha interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. NFKB inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in NFKBIA have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

The Abbkine IκB-α (phospho Ser32/S36) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of IκB-α protein only when phosphorylated at S32/S36. The antibody has been validaed in WB, IHC-P, IF, ELISA and reacts with Human, Mouse, Rat, Monkey samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-IκB-α (phospho Ser32/S36) Polyclonal Antibody at https://www.abbkine.com/product/iκb-α-phospho-ser32-s36-polyclonal-antibody-abp50346.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.