Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR encodes one of the two receptors of the VEGF.Kinase insert domain receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of KDR are implicated in infantile capillary hemangiomas.

The Abbkine Flk-1 (phospho Tyr1175) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of Flk-1 protein only when phosphorylated at Y1175. The antibody has been validaed in WB, IHC-P, ELISA and reacts with Human, Mouse, Rat samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Flk-1 (phospho Tyr1175) Polyclonal Antibody at https://www.abbkine.com/product/flk-1-phospho-tyr1175-polyclonal-antibody-abp50314.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.