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Catenin-β (phospho Ser37) Polyclonal Antibody
Catenin-β (phospho Ser37) Polyclonal Antibody
Origin of place China
Model ABP50278
Supplier Abbkine Scientific
Price $100
Hits 212
Updated 10/16/2019
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Catenin beta 1 encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta 1 also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, catenin beta 1 binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.

The Abbkine Catenin-β (phospho Ser37) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of Catenin-β protein only when phosphorylated at S37. The antibody has been validaed in WB, IHC-P, IF, ELISA and reacts with Human, Mouse, Rat samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-Catenin-β (phospho Ser37) Polyclonal Antibody at https://www.abbkine.com/product/catenin-β-phospho-ser37-polyclonal-antibody-abp50278.

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