CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. lysine acetyltransferase 2B associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that lysine acetyltransferase 2B plays a direct role in transcriptional regulation.

The Abbkine PCAF (Acetyl Lys428) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and synthesized peptide derived from the human PCAF around the acetylation site of K428. The antibody has been validaed in WB, ELISA and reacts with Human, Mouse samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-PCAF (Acetyl Lys428) Polyclonal Antibody at https://www.abbkine.com/product/pcaf-acetyl-lys428-polyclonal-antibody-abp50128.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.