CDKN1C is imprinted, with preferential expression of the maternal allele. Cyclin dependent kinase inhibitor 1C is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for CDKN1C.

The Abbkine p57 (Acetyl Lys278) Rabbit Polyclonal Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen anddetects endogenous levels of p57 protein only when acetylated at K278. The antibody has been validaed in WB, ELISA and reacts with Human, Mouse, Rat samples.

Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-p57 (Acetyl Lys278) Polyclonal Antibody at https://www.abbkine.com/product/p57-acetyl-lys278-polyclonal-antibody-abp50120.

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.