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Home >Products> Reagents >Antibody> Alexa Fluor庐 647 Rat Anti-Mouse CD63 Antibody (S-R667)
Alexa Fluor庐 647 Rat Anti-Mouse CD63 Antibody (S-R667)
Alexa Fluor庐 647 Rat Anti-Mouse CD63 Antibody (S-R667)
Origin of place Singapore
Model S0B5446-20T
Supplier ANT BIO PTE.LTD.
Price 110
Hits 8
Updated 9/1/2025
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Product Specification


HostRat
AntigenCD63
SynonymsCD63 antigen
LocationSecreted, Lysosome, Endosome, Cell membrane
AccessionP41731
Clone NumberS-R667
Antibody TypeRat mAb
IsotypeIgG2a,k
ApplicationICFCM
ReactivityMs
Positive SampleC57BL/6 mouse bone marrow cells
PurificationProtein G
Concentration0.05mg/ml
ConjugationAlexa Fluor庐 647
Physical AppearanceLiquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied.

Dilution


applicationdilutionspecies
ICFCM5渭l per million cells in 100渭l volumeMs

Background

CD63 is a tetraspanin protein involved in various cellular processes such as cell adhesion, migration, and signal transduction. It is predominantly found on the membranes of late endosomes, multivesicular bodies, and exosomes. As a marker protein of exosomes, CD63 plays a crucial role in cell-to-cell communication, including facilitating the interaction between tumor cells and surrounding cells. Additionally, CD63 is associated with intracellular secretory events in cells like eosinophils, where it is involved in degranulation processes. In some cancers, such as hepatocellular carcinoma, CD63-overexpressing tumor-associated macrophages can drive tumor progression by promoting cancer cell proliferation, migration, and invasion.

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