Product SpecificationHost | Mouse | Antigen | CD11c | Synonyms | Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; ITGAX | Location | Membrane | Accession | P20702 | Clone Number | S-R424 | Antibody Type | Mouse mAb | Isotype | IgG1,k | Application | FCM | Reactivity | Hu | Positive Sample | Human Peripheral Blood cells | Purification | Protein G | Concentration | 0.05mg/ml | Conjugation | Alexa Fluor庐 647 | Physical Appearance | Liquid | Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 | Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied. |
Dilutionapplication | dilution | species | FCM | 5渭l per million cells in 100渭l volume | Hu |
BackgroundCD11c is a type I transmembrane protein and a member of the 尾2 integrin family, primarily expressed on dendritic cells, monocytes, macrophages, neutrophils, and some B cells. It forms a heterodimer with CD18, known as integrin 伪X尾2. This molecule plays a crucial role in immune cell functions such as adhesion, phagocytosis, and cell migration. CD11c is also involved in the regulation of B cell homeostasis and the development of T cells in the thymus. Additionally, it has been implicated in the clearance of apoptotic cells by microglia during developmental apoptosis. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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