Product SpecificationHost | Rat | Antigen | CD63 | Synonyms | CD63 antigen | Location | Secreted, Lysosome, Endosome, Cell membrane | Accession | P41731 | Clone Number | S-R667 | Antibody Type | Rat mAb | Isotype | IgG2a,k | Application | ICFCM | Reactivity | Ms | Positive Sample | BALB/c mouse bone marrow | Purification | Protein G | Concentration | 2 mg/ml | Conjugation | Unconjugated | Physical Appearance | Liquid | Storage Buffer |
PBS聽pH7.4
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied. |
Dilutionapplication | dilution | species | ICFCM | 1:2000 | Ms |
BackgroundCD63 is a tetraspanin protein involved in various cellular processes such as cell adhesion, migration, and signal transduction. It is predominantly found on the membranes of late endosomes, multivesicular bodies, and exosomes. As a marker protein of exosomes, CD63 plays a crucial role in cell-to-cell communication, including facilitating the interaction between tumor cells and surrounding cells. Additionally, CD63 is associated with intracellular secretory events in cells like eosinophils, where it is involved in degranulation processes. In some cancers, such as hepatocellular carcinoma, CD63-overexpressing tumor-associated macrophages can drive tumor progression by promoting cancer cell proliferation, migration, and invasion. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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