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Rat Anti-Mouse CD63 Antibody (S-R667)
Rat Anti-Mouse CD63 Antibody (S-R667)
Origin of place Singapore
Model S0B5294-25μl
Supplier ANT BIO PTE.LTD.
Price 100
Hits 9
Updated 9/1/2025
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Product Specification


HostRat
AntigenCD63
SynonymsCD63 antigen
LocationSecreted, Lysosome, Endosome, Cell membrane
AccessionP41731
Clone NumberS-R667
Antibody TypeRat mAb
IsotypeIgG2a,k
ApplicationICFCM
ReactivityMs
Positive SampleBALB/c mouse bone marrow
PurificationProtein G
Concentration2 mg/ml
ConjugationUnconjugated
Physical AppearanceLiquid
Storage Buffer

PBS聽pH7.4

Stability & Storage12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied.

Dilution


applicationdilutionspecies
ICFCM1:2000Ms

Background

CD63 is a tetraspanin protein involved in various cellular processes such as cell adhesion, migration, and signal transduction. It is predominantly found on the membranes of late endosomes, multivesicular bodies, and exosomes. As a marker protein of exosomes, CD63 plays a crucial role in cell-to-cell communication, including facilitating the interaction between tumor cells and surrounding cells. Additionally, CD63 is associated with intracellular secretory events in cells like eosinophils, where it is involved in degranulation processes. In some cancers, such as hepatocellular carcinoma, CD63-overexpressing tumor-associated macrophages can drive tumor progression by promoting cancer cell proliferation, migration, and invasion.

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