Product SpecificationHost | Mouse | Antigen | CD8伪 | Synonyms | T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; MAL; CD8A | Location | Secreted, Cell membrane | Accession | P01732 | Clone Number | S-R533 | Antibody Type | Mouse mAb | Isotype | IgG1 | Application | FCM | Reactivity | Hu | Positive Sample | human peripheral blood lymphocytes | Purification | Protein G | Concentration | 0.2 mg/ml | Conjugation | Biotin | Physical Appearance | Liquid | Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 | Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied. |
Dilutionapplication | dilution | species | FCM | 0.5渭l per million cells in 100渭l volume | Hu |
BackgroundCD8伪 is a crucial immune glycoprotein that plays a vital role in the immune response by serving as a co-receptor for the T-cell receptor (TCR) on cytotoxic T cells. It forms either a homodimer (伪/伪) or a heterodimer with CD8尾 (伪/尾) to interact with MHC class I molecules on antigen-presenting cells (APCs), facilitating the recognition of intracellular pathogens such as viruses. CD8伪 also recruits the LCK kinase, which initiates downstream signaling pathways essential for T-cell activation and proliferation. This molecule is critical for the function of cytotoxic T lymphocytes (CTLs) and is involved in various immune-related diseases, including immunodeficiencies and autoimmune conditions. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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