Product SpecificationHost | Rat | Antigen | CD8伪 | Synonyms | T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein Lyt-2; Lyt-2; Lyt2 | Location | Cell membrane | Accession | P01731 | Clone Number | S-R540 | Antibody Type | Rat mAb | Isotype | IgG2a,k | Application | FCM | Reactivity | Ms | Positive Sample | C57BL/6 mouse splenocytes | Purification | Protein G | Concentration | 0.02mg/ml | Conjugation | Biotin | Physical Appearance | Liquid | Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 | Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied. |
Dilutionapplication | dilution | species | FCM | 5渭l per million cells in 100渭l volume | Ms |
BackgroundCD8伪 is a crucial immune glycoprotein that serves as a co-receptor for the MHC I-peptide complex, facilitating the recognition of antigens presented by APCs (antigen-presenting cells) to T cells. It is a key component of the CD8 receptor complex, which is predominantly found on cytotoxic T lymphocytes (CTLs). CD8伪 can form either an 伪/尾 heterodimer with CD8尾 or an 伪/伪 homodimer, both of which play essential roles in CTL activation and function. By interacting with the TCR (T cell receptor) and MHC I molecules, CD8伪 helps recruit the LCK kinase, initiating multiple signaling pathways that drive the CTL-mediated immune response. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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