Product SpecificationHost | Rabbit | Antigen | CXCL10/IP-10 | Synonyms | 10 kDa interferon gamma-induced protein (Gamma-IP10; IP-10)
Small-inducible cytokine B10 | Immunogen | Recombinant Protein | Accession | P02778 | Clone Number | SDT-1910-35 | Antibody Type | Recombinant mAb | Isotype | IgG | Application | Sandwich ELISA | Reactivity | Hu | Cross Reactivity | No cross-reactivity against GRO alpha, GRO beta, MCP-1 | Purification | Protein A | Concentration | 2 mg/ml | Conjugation | Unconjugated | Physical Appearance | Liquid | Storage Buffer | PBS pH7.4, 0.03% Proclin 300 | Stability & Storage | 12 months from date of receipt, 2 to 8 掳C as supplied |
BackgroundCXCL10, also known as interferon 纬-induced protein 10 kDa (IP-10), is a cytokine belonging to the CXC chemokine family. It exerts its biological effects by binding to the CXCR3 receptor and plays a crucial role in immune responses. CXCL10 is a pleiotropic molecule with diverse functions, including promoting the chemotaxis of CXCR3+ cells, inducing apoptosis, regulating cell growth and proliferation, and modulating angiogenesis in infectious diseases, inflammation, and cancer. It is primarily produced by various cell types in response to IFN-纬 and is involved in activating T lymphocytes, NK cells, macrophages, dendritic cells, and B cells. Elevated levels of CXCL10 are associated with several pathological conditions, such as autoimmune diseases, viral infections, and tumor development. bio-equip.cn
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