Alexa Fluor® 647 Mouse Anti-Human CD59 Antibody (S-R567),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Mouse
Antigen	Human CD59
Synonyms	CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor (HRF-20; HRF20); MAC-inhibitory protein (MAC-IP); MEM43 antigen; Membrane attack complex inhibition factor (MACIF); Membrane inhibitor of reactive lysis (MIRL); Protectin
Location	Cell membrane
Accession	P13987
Clone Number	S-R567
Antibody Type	Mouse mAb
Isotype	IgG2a
Application	FCM
Reactivity	Hu
Positive Sample	Human peripheral blood
Purification	Protein A
Concentration	0.05mg/ml
Conjugation	Alexa Fluor® 647
Physical Appearance	Liquid
Storage Buffer	PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
FCM	5μl per million cells in 100μl volume	Hu

Background

CD59, also known as protectin, is a glycosylphosphatidylinositol (GPI)-anchored protein expressed on the surface of various cells. It plays a vital role in regulating the immune system and protecting cells from the complement system. Specifically, CD59 is the only membrane-bound inhibitor of the complement membrane attack complex (MAC), an immune pore that can damage human cells. Without CD59, MAC pores formed on red blood cells result in rupture, causing chronic hemolysis and immune-related neuropathies.