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Home >Products> Reagents >Antibody> Crotonyllysine Rabbit Polyclonal Antibody
Crotonyllysine Rabbit Polyclonal Antibody
Crotonyllysine Rabbit Polyclonal Antibody
Origin of place Singapore
Model S0B1324-25μl
Supplier ANT BIO PTE.LTD.
Price 160
Hits 5
Updated 8/27/2025
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Product Specification


HostRabbit
AntigenCrotonyllysine
ImmunogenSynthetic Peptide
Antibody TypePolyclonal antibody
IsotypeIgG
ApplicationWB
PurificationProtein A
Concentration5 mg/ml
ConjugationUnconjugated
Physical AppearanceLiquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


applicationdilutionspecies
WB1:1000Ms

Background

Crotonyllysine is a post-translational modification of protein lysine residues, characterized by the addition of a crotonyl group. This modification plays a crucial role in various cellular processes, including gene transcription, acute kidney injury, and spermatogenesis. The dynamic balance of crotonyllysine modification is regulated by a set of enzymes, including "writers" that add the modification and "erasers" that remove it. Crotonyl-CoA, the primary precursor for crotonyllysine modification, is influenced by the activity of enzymes such as ACSS2 and CDYL. Abnormal levels of crotonyl-CoA and crotonyllysine have been implicated in several diseases, including cancer and cardiovascular diseases, making it an important area of research for future therapeutic strategies.

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