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Rat Anti-Mouse CD44 Antibody (S-923-31)
Rat Anti-Mouse CD44 Antibody (S-923-31)
Origin of place Singapore
Model S0B1318-25μl
Supplier ANT BIO PTE.LTD.
Price 100
Hits 4
Updated 8/27/2025
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Product Specification


HostRat
AntigenCD44
SynonymsCD44 antigen; Extracellular matrix receptor III (ECMR-III); GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Lymphocyte antigen 24 (Ly-24); Phagocytic glycoprotein 1 (PGP-1); Phagocytic glycoprotein I (PGP-I); Ly-24
ImmunogenRecombinant Protein
LocationSecreted, Cell membrane
AccessionP15379
Clone NumberS-923-31
Antibody TypeRat mAb
IsotypeIgG2a,k
ApplicationICC, FCM
ReactivityMs
Positive SampleC2C12
Concentration1.5 mg/ml
Physical AppearanceLiquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8°C as supplied

Dilution


applicationdilutionspecies
ICC1:500Ms
FCM1:150Ms

Background

CD44 is a transmembrane glycoprotein that plays a crucial role in cell-cell and cell-matrix interactions. It is widely expressed on various cell types, including endothelial cells, epithelial cells, fibroblasts, and leukocytes. The molecule is composed of an extracellular domain, a transmembrane domain, and an intracellular domain, with the extracellular domain being responsible for binding to ligands such as hyaluronic acid (HA), which is its primary ligand. CD44 is involved in numerous physiological processes, including cell adhesion, migration, proliferation, and immune cell activation. Additionally, it plays a significant role in cancer progression, as it is often overexpressed in cancer cells and contributes to tumor growth, invasion, and metastasis. The diverse functions of CD44 are attributed to its various isoforms, which result from alternative splicing and post-translational modifications.

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