Product SpecificationHost | Rat | Antigen | CD44 | Synonyms | CD44 antigen; Extracellular matrix receptor III (ECMR-III); GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Lymphocyte antigen 24 (Ly-24); Phagocytic glycoprotein 1 (PGP-1); Phagocytic glycoprotein I (PGP-I); Ly-24 | Immunogen | Recombinant Protein | Location | Secreted, Cell membrane | Accession | P15379 | Clone Number | S-923-31 | Antibody Type | Rat mAb | Isotype | IgG2a,k | Application | ICC, FCM | Reactivity | Ms | Positive Sample | C2C12 | Concentration | 1.5 mg/ml | Physical Appearance | Liquid | Storage Buffer | PBS pH7.4 | Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8°C as supplied |
Dilutionapplication | dilution | species | ICC | 1:500 | Ms | FCM | 1:150 | Ms |
BackgroundCD44 is a transmembrane glycoprotein that plays a crucial role in cell-cell and cell-matrix interactions. It is widely expressed on various cell types, including endothelial cells, epithelial cells, fibroblasts, and leukocytes. The molecule is composed of an extracellular domain, a transmembrane domain, and an intracellular domain, with the extracellular domain being responsible for binding to ligands such as hyaluronic acid (HA), which is its primary ligand. CD44 is involved in numerous physiological processes, including cell adhesion, migration, proliferation, and immune cell activation. Additionally, it plays a significant role in cancer progression, as it is often overexpressed in cancer cells and contributes to tumor growth, invasion, and metastasis. The diverse functions of CD44 are attributed to its various isoforms, which result from alternative splicing and post-translational modifications. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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