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Home >Products> Reagents >Antibody> Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) (SDT-R041)
Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) (SDT-R041)
Lamin A/C Recombinant Rabbit mAb (HRP Conjugate) (SDT-R041)
Origin of place Singapore
Model S0B1820-25μl
Supplier ANT BIO PTE.LTD.
Price 80
Hits 4
Updated 8/27/2025
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Product Specification


HostRabbit
AntigenLamin A/C
SynonymsPrelamin-A/C; 70 kDa lamin, Renal carcinoma antigen NY-REN-32; LMN1; LMNA
LocationNucleus
AccessionP02545
Clone NumberSDT-R041
Antibody TypeRecombinant mAb
IsotypeIgG
ApplicationWB
ReactivityHu
Positive SampleHeLa, HUVEC, HepG2
PurificationProtein A
Concentration2 mg/ml
ConjugationHRP
Physical AppearanceLiquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage12 months from date of receipt / reconstitution, -20 °C as supplied.

Dilution


applicationdilutionspecies
WB1:5000-1:10000Hu

Background

Lamin A/C is a crucial nuclear protein encoded by the LMNA gene, playing a significant role in maintaining the structural integrity of the cell nucleus. It is part of the nuclear lamina, a fibrous layer that provides support to the nuclear envelope and helps in organizing the chromatin. Beyond its structural function, lamin A/C is involved in various cellular processes, including gene regulation, DNA replication and repair, cell differentiation, and mechanosensing. Mutations in the lamin A/C gene can lead to a range of diseases collectively known as laminopathies, which include muscular dystrophy, lipodystrophy, and certain forms of cardiomyopathy. Additionally, lamin A/C has been implicated in cancer, where its deregulation can contribute to genomic instability and affect the mechanical resilience of tumor cells.

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