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Home >Products> Reagents >Antibody> Rat Anti-Mouse CD186 antibody (S-R602)
Rat Anti-Mouse CD186 antibody (S-R602)
Rat Anti-Mouse CD186 antibody (S-R602)
Origin of place Singapore
Model S0B1300-25μl
Supplier ANT BIO PTE.LTD.
Price 100
Hits 4
Updated 8/27/2025
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Product Specification


HostRat
AntigenMouse CD186
SynonymsC-X-C chemokine receptor type 6; CXC-R6; CXCR-6; Cxcr6
LocationCell membrane
AccessionQ9EQ16
Clone NumberS-R602
Antibody TypeRat mAb
IsotypeIgG2b,k
ApplicationFCM
ReactivityMs
Positive SampleC57BL/6 mouse splenocytes
PurificationProtein G
Concentration2 mg/ml
ConjugationUnconjugated
Physical AppearanceLiquid
Storage BufferPBS pH7.4
Stability & Storage12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


applicationdilutionspecies
FCM1:200Ms

Background

CD186, also known as CXCR6, is a G protein-coupled chemokine receptor with seven transmembrane domains. It is expressed on activated and memory T cells and its ligand is the chemokine CXCL16. CXCR6 plays a role in the recruitment of cells to inflamed sites and is also a coreceptor for HIV-1 and SIV to enter target cells, in conjunction with CD4. This receptor is involved in the regulation of T lymphocyte migration to various peripheral tissues and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. Additionally, CXCR6/CCL16 controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are crucial for defense against respiratory pathogens.

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