Product SpecificationHost | Rabbit | Antigen | SNAP25 | Synonyms | Synaptosomal-associated protein 25; Super protein (SUP); SNAP-25; Synaptosomal-associated 25 kDa protein; SNAP | Immunogen | Synthetic Peptide | Location | Cytoplasm, Cell membrane | Accession | P60880 | Clone Number | S-1828-67 | Antibody Type | Recombinant mAb | Isotype | IgG | Application | WB, IHC-P, IF | Reactivity | Hu, Ms, Rt | Positive Sample | Human brain, mouse brain, rat brain | Predicted Reactivity | Mq, Gor, Gfs, Zf | Purification | Protein A | Concentration | 0.5 mg/ml | Conjugation | Unconjugated | Physical Appearance | Liquid | Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 | Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilutionapplication | dilution | species | WB | 1:1000-1:10000 | Ms,Rt | IHC-P | 1:500 | Hu, Ms, Rt | IF | 1:500 | Hu, Ms |
BackgroundSNAP25, or synaptosomal-associated protein 25, is a crucial component of the SNARE complex that plays a pivotal role in the molecular regulation of neurotransmitter release. It is primarily associated with the presynaptic membrane and is involved in vesicle docking and membrane fusion, which are essential for the release of neurotransmitters into the synaptic cleft. Recent research has also suggested a potential postsynaptic role for SNAP25, indicating its presence in the postsynaptic density (PSD), postsynaptic lateral membrane, and small vesicles in the postsynaptic cytoplasm, which may be implicated in synaptic plasticity. Furthermore, SNAP25 has been linked to the modulation of the gating characteristics of certain ion channels, such as the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. Its expression and structural abnormalities have been reported in various neurological disorders, emphasizing its importance in synaptic function and neurological health. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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