Product SpecificationHost | Rabbit | Antigen | Transferrin | Synonyms | Serotransferrin; Beta-1 metal-binding globulin; Siderophilin; TF | Immunogen | Synthetic Peptide | Location | Secreted | Accession | P02787 | Clone Number | S-1611-43 | Antibody Type | Recombinant mAb | Isotype | IgG | Application | WB, IHC-P | Reactivity | Hu | Predicted Reactivity | Cz | Purification | Protein A | Concentration | 0.5 mg/ml | Conjugation | Unconjugated | Physical Appearance | Liquid | Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 | Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilutionapplication | dilution | species | WB | 1:1000 | Hu | IHC-P | 1:250 | Hu |
BackgroundTransferrin, also known as TRF or Tf, is a major glycoprotein in the plasma of vertebrates that plays a critical role in the transport and metabolism of iron ions. It is synthesized mainly in the liver and is responsible for carrying iron absorbed from the digestive tract and iron released from the degradation of red blood cells. Transferrin enters the bone marrow in the form of TRF-Fe3+ complex, supplying iron for the production of mature red blood cells. This protein can carry two trivalent iron ions (Fe3+) per molecule and interacts with Fe3+ depending on pH; it binds Fe3+ efficiently at pH 7.4 and releases it under acidic conditions. Transferrin also has several physiological and biochemical functions, including antimicrobial activity, involvement in immune system cell protection, and regulation of cell proliferation. Moreover, it serves as a novel active targeting carrier in the field of tumor targeting, showing promise for future applications. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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