FITC Rat Anti-Mouse CD8α Antibody (S-R540),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Rat
Antigen	mouse CD8α
Synonyms	Lyt-2
Location	Cell membrane
Accession	P01731
Clone Number	S-R540
Antibody Type	Rat mAb
Isotype	IgG2a,k
Application	FCM
Reactivity	Ms
Positive Sample	C57BL/6 mouse splenocytes
Purification	Protein G
Concentration	0.05mg/ml
Conjugation	FITC
Physical Appearance	Liquid
Storage Buffer	PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
FCM	5 μl per million cells in 100μl volume	Ms

Background

CD8α encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.