Argonaute-2 Recombinant Rabbit mAb (S-1826-47),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	Argonaute-2
Synonyms	Protein argonaute-2; hAgo2; Argonaute2; Argonaute RISC catalytic component 2; Eukaryotic translation initiation factor 2C (eIF-2C; eIF2C 2); PAZ Piwi domain protein (PPD); Protein slicer; AGO2;
Immunogen	Synthetic Peptide
Location	Cytoplasm, Nucleus
Accession	Q9UKV8
Clone Number	S-1826-47
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P, ICC
Reactivity	Hu, Ms, Rt
Positive Sample	HeLa, Jurkat, MCF7, HepG2, U-87 MG, RAW264.7, C6
Predicted Reactivity	Bv, Rb, Xe,
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:2000	Hu, Ms, Rt
IHC-P	1:200	Hu, Ms, Rt
ICC	1:500	Hu

Background

Argonaute-2 (AGO2) is a pivotal protein in the RNA interference and microRNA pathways, known for its role in gene regulation through the binding and cleavage of target mRNAs, which it achieves by forming the RNA-induced silencing complex (RISC) with small RNAs such as siRNA and miRNA. This process is essential for post-transcriptional gene regulation, immune defense, and plays a significant role in various biological processes including development, cell differentiation, and tumorigenesis.