Product SpecificationHost | Rabbit | Antigen | 14-3-3 zeta | Synonyms | Protein kinase C inhibitor protein 1 (KCIP-1); YWHAZ | Immunogen | Recombinant Protein | Location | Cytoplasm, Melanosome | Accession | P63104 | Clone Number | S-1092-31 | Antibody Type | Recombinant mAb | Isotype | IgG | Application | WB, IHC-P, ICC | Reactivity | Hu, Ms, Rt | Positive Sample | HeLa, SH-SY5Y, Jurkat, NIH/3T3, rat brain | Predicted Reactivity | Cw, Ck, Sh, Fr | Purification | Protein A | Concentration | 2 mg/ml | Conjugation | Unconjugated | Physical Appearance | Liquid | Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 | Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilutionapplication | dilution | species | WB | 1:1000 | Hu, Ms, Rt | IHC-P | 1:500 | Hu, Ms | ICC | 1:500 | Hu, Ms |
BackgroundThe 14-3-3 zeta protein, also known as YWHAZ, is a member of the 14-3-3 protein family, which consists of highly conserved acidic proteins with molecular weights ranging from 28 to 33 kDa. The 14-3-3 zeta protein plays a significant role in cells, participating in the regulation of many key cellular life activities, including metabolism, cell cycle, cell growth and development, cell survival and apoptosis, and gene transcription. Moreover, the 14-3-3 zeta protein is closely associated with the occurrence and development of various diseases, especially neurological disorders and cancers. In cancers, the expression level of 14-3-3 zeta protein is correlated with poor patient prognosis, including breast cancer, lung cancer, multiple myeloma, head and neck cancer, and glioblastoma, among others. The 14-3-3 zeta protein is also related to chemoresistance in tumors, with its overexpression increasing the resistance of tumor cells to chemotherapy drugs. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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