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Home >Products> Reagents >Antibody> ENPP3/CD203c Recombinant Rabbit mAb (S-1632-11)
ENPP3/CD203c Recombinant Rabbit mAb (S-1632-11)
ENPP3/CD203c Recombinant Rabbit mAb (S-1632-11)
Origin of place Singapore
Model S0B1115-25μl
Supplier ANT BIO PTE.LTD.
Price 100
Hits 3
Updated 8/27/2025
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Product Specification


HostRabbit
AntigenENPP3/CD203c
SynonymsEctonucleotide pyrophosphatase/phosphodiesterase family member 3; E-NPP 3; NPP3; Alkaline phosphodiesterase I; Dinucleoside polyphosphatase; Nucleotide diphosphatase; Nucleotide pyrophosphatase (NPPase); Phosphodiesterase I beta (PD-Ibeta); Phosphodiesterase I/nucleotide pyrophosphatase 3; PDNP3
ImmunogenSynthetic Peptide
LocationCell membrane, Secreted
AccessionO14638
Clone NumberS-1632-11
Antibody TypeRecombinant mAb
IsotypeIgG
ApplicationWB, IHC-P, IF
ReactivityHu, Ms
Positive SampleKU-812, Neruo-2a, mouse kidney
Predicted ReactivityP. abelii
PurificationProtein A
Concentration0.5 mg/ml
ConjugationUnconjugated
Physical AppearanceLiquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


applicationdilutionspecies
WB1:1000Hu, Ms
IHC-P1:250Hu, Ms
IF1:500Hu

Background

ENPP3 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 3) is a type II transmembrane protein belonging to the membrane-bound ectonucleotide pyrophosphatase/phosphodiesterase family (ENPPs/ENPPs). ENPP3 is involved in nucleotide signaling, particularly in regulating allergic responses in basal cells and mast cells, and serves as a potential biomarker for allergen sensitivity. Under pathological conditions, ENPP3 is overexpressed in various cancers, including renal cell carcinoma, hepatocellular carcinoma, colorectal cancer, and cholangiocarcinoma, making it a potential tumor marker and therapeutic target. ENPP3 is recognized as a major cGAMP hydrolase, which is a second messenger synthesized after the detection of cytosolic double-stranded DNA and is transmitted intercellularly to promote downstream immune signaling. Like ENPP1, ENPP3 inhibits anti-tumor immune responses by hydrolyzing cGAMP.

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