Claudin 1 Recombinant Rabbit mAb (SDT-1289-55),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	Claudin 1
Synonyms	Senescence-associated epithelial membrane protein; CLDN1; CLD1, SEMP1
Immunogen	Synthetic Peptide
Location	Cell membrane
Accession	O95832
Clone Number	SDT-1289-55
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P, IF
Reactivity	Hu
Positive Sample	MCF7, A431, HepG2, mouse skin, rat kidney
Predicted Reactivity	Bv
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000	Hu, Ms, Rt
IHC-P	1:250	Hu
IF	1:200	Hu

Background

Claudin 1 is a 23 kDa multi-pass membrane protein in the Claudin family of epithelial tight junction proteins. Claudin-1 is expressed by epithelial cells in a wide variety of tissues as well as in Langerhans cells and dendritic cells. It is up or downregulated in many cancers and is required for the entry of hepatitis C virus into hepatocytes. It mainly expresses the peripheral neuroma (partial type of negative), derivative skin fibrous sarcoma, fibroma and deity fibroma.