Product Specification| Host | Rabbit | | Antigen | Phospho-PDK1/PDPK1-S241 | | Synonyms | 3-phosphoinositide-dependent protein kinase 1 | | Immunogen | Synthetic Peptide | | Location | Cytoplasm, Nucleus | | Accession | O15530 | | Clone Number | S-1426-93 | | Antibody Type | Recombinant mAb | | Isotype | IgG | | Application | WB | | Reactivity | Ms | | Positive Sample | NIH/3T3 | | Predicted Reactivity | Hu | | Purification | Protein A | | Concentration | 0.5 mg/ml | | Conjugation | Unconjugated | | Physical Appearance | Liquid | | Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 | | Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution| application | dilution | species | | Dot Blot | 1:1000 | | | WB | 1:1000 | Ms |
BackgroundPhospho-PDK1 (Ser241) refers to the protein PDK1 that is phosphorylated at the Ser241 site. PDK1, full name 3-phosphoinositide-dependent protein kinase-1, is a serine/threonine protein kinase that plays a central role in regulating cell growth, survival, and proliferation. Overexpression of PDK1 in cells has been observed in breast and ovarian cancers, and its activity increases in prion-infected neurons. Phosphorylation of a conserved serine (S241) in the activation loop leads to the activation of PDK1. bio-equip.cn AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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