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DAZL Recombinant Rabbit mAb (S-1552-6)
DAZL Recombinant Rabbit mAb (S-1552-6)
Origin of place Singapore
Model S0B0940-25μl
Supplier ANT BIO PTE.LTD.
Price 100
Hits 2
Updated 8/27/2025
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Product Specification


HostRabbit
AntigenDAZL
SynonymsDeleted in azoospermia-like, DAZ-like autosomal, Deleted in azoospermia-like 1, Dazl1, Dazla
ImmunogenSynthetic Peptide
LocationCytoplasm
AccessionQ64368
Clone NumberS-1552-6
Antibody TypeRecombinant mAb
IsotypeIgG
ApplicationWB, IHC-P, IF
ReactivityMs, Rt
PurificationProtein A
Concentration0.5 mg/ml
ConjugationUnconjugated
Physical AppearanceLiquid
Storage BufferPBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


applicationdilutionspecies
WB1:1000null
IHC-P1:2000null
IF1:2000null

Background

DAZL, or Deleted in Azoospermia-Like, is an RNA-binding protein that plays a critical role in germ cell development and maturation. It is highly expressed in primordial germ cells (PGCs) and is essential for their proper development and function. DAZL has been shown to regulate gene expression at both the transcriptional and post-transcriptional levels. It interacts with specific sequences in the 3' untranslated regions (UTRs) of target mRNAs, thereby influencing their stability, translation, and ultimately, their contribution to the germ cell's proteome. Recent research has uncovered additional layers of DAZL's functionality. It can also bind to microRNA (miRNA) precursors and enhance the processing activity of Dicer, an enzyme crucial for miRNA maturation. This discovery expands the known mechanisms by which DAZL can modulate gene expression and suggests that it may have a broader role in regulating cellular processes than previously understood.

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