Login    Join free Add to favorites    中文
Home >Products> Reagents >Antibody> DAZL Rabbit Polyclonal Antibody
DAZL Rabbit Polyclonal Antibody
DAZL Rabbit Polyclonal Antibody
Origin of place Singapore
Model S0B0915-10μl
Supplier ANT BIO PTE.LTD.
Price 35
Hits 1
Updated 8/27/2025
  • Product Detail
  • Company Profile

Product Specification


HostRabbit
AntigenDAZL
SynonymsDeleted in azoospermia-like; DAZ-like autosomal; Deleted in azoospermia-like 1; Dazl1; Dazla
ImmunogenSynthetic Peptide
LocationCytoplasm
AccessionQ64368
IsotypeIgG
ApplicationWB, IHC-P, IF, IP
ReactivityHu, Ms, Rt
PurificationProtein A
Concentration0.5 mg/ml
ConjugationUnconjugated
Physical AppearanceLiquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


applicationdilutionspecies
WB1:1000
IP1:50
IHC-P1:250
IF1:250

Background

DAZL, or Deleted in Azoospermia-Like, is an RNA-binding protein that plays a pivotal role in germ cell development and oocyte maturation. It is specifically expressed in germ cells and is essential for their proper differentiation and function. DAZL has been shown to regulate the translation of a variety of mRNAs, thereby controlling the expression of proteins critical for germ cell development. Recent studies have revealed that DAZL can function as both a repressor and activator of mRNA translation, depending on the context and the specific mRNA targets. It interacts with the 3' untranslated regions (UTRs) of its target mRNAs, modulating their stability and translation efficiency. DAZL's dual role in translational control is significant for understanding the molecular mechanisms underlying germ cell maturation and early embryonic development. The protein's function is so critical that its absence or mutation can lead to infertility, as seen in certain cases of male azoospermia.

bio-equip.cn
Request Infomation

* Name:
Title:
* Tel:
Fax:
* E-mail:
Postcode:
Institution/Company:
Address:
* Country:
Request infomation:
yes no
Request Quotation:
yes no
* Message:
Validated Code:
refresh
I agree to share my inquiry to the other matching suppliers.



Copyright(C) 2006-2025 Bio-Equip    E-mail:web@bio-equip.cn   沪ICP备06040519号