VISTA Recombinant Rabbit mAb (S-1469-72),specification,price,image-Bio-Equip in China

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	VISTA
Synonyms	V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; Stress-induced secreted protein-1 (Sisp-1); V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; C10orf54; SISP1
Immunogen	Recombinant Protein
Location	Cell membrane
Accession	Q9H7M9
Clone Number	S-1469-72
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P, IP, FCM
Reactivity	Hu
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IP	1:50
IHC-P	1:250
FCM	1:50

Background

VISTA is an important immune modulatory receptor that is gaining attention in cancer immunotherapy. VISTA exerts its suppressive effects on T cell activity by binding to their respective ligands on T cells, potentially influencing the immune evasion mechanisms of tumors. Studies have shown that VISTA is expressed in a variety of cancers, including melanoma, pancreatic cancer, and prostate cancer, and its expression levels are closely related to the immunosuppressive state of tumors.