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Home >Products> Reagents >Antibody> Invivo anti-mouse Ly6G/Ly6C (Gr-1) (S-R425)
Invivo anti-mouse Ly6G/Ly6C (Gr-1) (S-R425)
Invivo anti-mouse Ly6G/Ly6C (Gr-1) (S-R425)
Origin of place Singapore
Model S0B0838-1mg
Supplier ANT BIO PTE.LTD.
Price 170
Hits 1
Updated 8/27/2025
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Product Specification


HostRat
AntigenMouse Ly-6G/Ly-6C (Gr-1)
SynonymsLymphocyte antigen 6G, Ly-6G.1
LocationCell membrane
AccessionP35461
Clone NumberS-R425
Antibody TypeRecombinant mAb
IsotypeRat IgG2b,k
Applicationin vivo depletion of Gr-1+ myeloid cells
ReactivityMs
PurificationProtein G
Concentration5 mg/ml
Endotoxin<1EU/mg
ConjugationUnconjugated
Physical AppearanceLiquid
Storage Buffer

PBS pH7.4, containing no preservative

Stability & Storage

2 to 8 °C for 2 weeks under sterile conditions;

-20 °C for 3 months under sterile conditions; 

-80 °C for 24 months under sterile conditions.

Please avoid repeated freeze-thaw cycles.

Background

This antibody recognizes the same epitope as clone RB6-8C5. Ly-6G protein is a GPI (glycosylphosphatidylinositol)-anchored protein. Ly-6G is primarily expressed on monocytes, neutrophils, and T cells. It plays a crucial role in inhibiting anti-tumor efficacy and T-cell responses. Due to its specific expression on neutrophils, Ly-6G has been widely used as a surface marker in flow cytometry, cell sorting, and immune phenotyping experiments. Unique expression of Ly-6G in bone marrow indicates its involvement in hematopoietic microenvironment, potentially regulating the development or function of immune cells within the bone marrow niche.

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