SDHB Recombinant Rabbit mAb (SDT-1162-2),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	SDHB
Synonyms	Mitochondrial succinate dehydrogenase [ubiquinone] iron-sulfur subunit, Iron-sulfur subunit of complex II (Ip)
Immunogen	Synthetic Peptide
Accession	P21912
Clone Number	SDT-1162-2
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P, ICC, ICFCM, IF
Reactivity	Hu, Ms, Rt
Predicted Reactivity	Xe, Pg, Bv
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IHC-P	1:250-1:500
ICC	1:500
ICFCM	1:500
IF	1:200

Background

Succinate dehydrogenase B (SDHB) protein is an integral part of the complex II oxidation/reduction pathway. Its function is to transfer electrons from succinate to coenzyme Q.SDHB can be used to differentiate between type 1 (SDHB +) and type 2 (SDHB -) gastrointestinal stromal tumors (GIST).SDHB immunohistochemistry has emerged as a reliable method for diagnosing and screening of SDH-deficient tumors, including SDH-deficient pheochromocytoma/paraganglioma, SDH-deficient GIST, and SDH-deficient renal cell carcinoma.