PHOX2B Recombinant Rabbit mAb (SDT-1142-21),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Synonyms	Paired mesoderm homeobox protein 2B, Neuroblastoma Phox (NBPhox), PHOX2B homeodomain protein, Paired-like homeobox 2B, PMX2B
Immunogen	Synthetic Peptide
Location	Nucleus
Accession	Q99453
Clone Number	SDT-1142-21
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P
Reactivity	Hu, Ms, Rt
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IHC-P	1:200-1:500

Background

PHOX2B is a homeodomain transcription factor that is mainly expressed in neuronal cells of the peripheral autonomic nervous system, and plays a key role in the differentiation of neurons and chromaffin cells, in particular. PHOX2B has high sensitivity and specificity in neuroblastoma tissues. In addition, it is directly related to autonomic nervous system diseases that may occur with neuroblastoma (such as congenital megacolon and congenital central hypoventilation syndrome).