Invivo anti-mouse VEGFR-2 Recombinant mAb,specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Rat
Synonyms	Vascular endothelial growth factor receptor 2, Fetal liver kinase 1 (FLK-1), Kinase NYK, Protein-tyrosine kinase receptor flk-1, CD309, Kdr, Flk-1, Flk1
Accession	P35918
Clone Number	DC101
Antibody Type	Rat mAb
Application	WB, in vivo blocking of VEGF/VEGFR-2 signaling, in vitro blocking of VEGFR signaling
Reactivity	Ms
Purification	Protein G
Concentration	5 mg/ml
Endotoxin	<1EU/mg
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, containing no preservative
Stability & Storage	2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

Dilution

application	dilution	species
WB	1:500

Background

VEGFR-2 protein, also known as Vascular Endothelial Growth Factor Receptor 2 (VEGFR2 or KDR), is a crucial type III receptor tyrosine kinase that plays a pivotal role in regulating angiogenesis, vascular development, permeability, and embryonic hematopoiesis. Specifically, VEGFR-2 is a cell surface receptor for VEGFA, VEGFC, and VEGFD. It actively promotes endothelial cell proliferation, survival, migration, differentiation, and actin cytoskeleton reorganization. Furthermore, VEGFR-2 mediates VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting, which are essential processes in vasculogenesis and angiogenesis.