Invivo anti-mouse CTLA-4 (CD152) mAb,specification,price,image-Bio-Equip in China

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Product Specification

Host	Mouse
Synonyms	Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Location	Cell membrane
Accession	P09793
Clone Number	9D9
Antibody Type	Recombinant mAb
Isotype	IgG2b,k
Application	WB, in vivo CTLA-4 neutralizatior
Reactivity	Ms
Purification	Protein A
Concentration	Lot specific* (generally 5 to 20 mg/ml)*
Endotoxin	<1EU/mg
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, containing no preservative
Stability & Storage	2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

Dilution

application	dilution	species
WB	1:1000

Background

This antibody recognizes the same epitope as clone 9D9.

Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA-4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. CTLA-4 may also function via modulation of cell motility and/or signaling through PI3 kinase.