NA/LE Rat anti-mouse CD3 Recombinant mAb,specification,price,image-Bio-Equip in China

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Product Specification

Host	Rat
Antigen	CD3
Synonyms	T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain, CD247, Cd3z, Tcrz
Location	Cell membrane
Accession	P24161
Clone Number	17A2
Antibody Type	Recombinant mAb
Isotype	Rat IgG2b, κ
Application	FCM, in vitro T cell stimulation/activation
Reactivity	Ms
Purification	Protein G
Concentration	Lot specific* (generally 0.5 to 5 mg/ml)*
Endotoxin	＜1EU/mg
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, containing no preservative
Stability & Storage	2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

Dilution

application	dilution	species
FCM	1:500

Background

This antibody recognizes the same epitope as clone 17A2.

The CD3 protein is a T-cell marker, a complex of four structurally distinct membrane glycoprotein isoforms, 20-50 kDa, comprising extracellular, transmembrane and intracellular domains. CD3 is associated with an heterodimer creating the T-cell receptor (TCR). The CD3 complex is responsible for mediating signal transduction to the internal environment upon antigenic recognition by TCR, causing T-cell proliferation and release of cytokines.