CSF-1R Recombinant Rabbit mAb (S-467-26),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Rabbit
Antigen	CSF-1R
Synonyms	Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, M-CSF-R, Proto-oncogene c-Fms, CD115, FMS
Immunogen	Synthetic Peptide
Location	Cell membrane
Accession	P07333
Clone Number	S-467-26
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P
Reactivity	Hu, Ms, Rt
Predicted Reactivity	Ct
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:500-1:1000
IHC-P	1:100

Background

Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34). CSF1R is highly expressed in myeloid cells, and CSF1R signaling is necessary for the survival, proliferation, and differentiation of many myeloid cell types in vivo and in vitro. CSF1R signaling is involved in many diseases and is targeted in therapies for cancer, neurodegeneration, and inflammatory bone diseases.