Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (Cluster of Differentiation 66c), is a member of the carcinoembryonic antigen (CEA) family. Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family are transmembrane glycoproteins that belong to the immunoglobulin superfamily. They are involved in several biological processes, such as cell growth, differentiation, cell recognition, immune response, and adhesion [7-10]. Different members of the CEACAM family may have different functions. There are four members of CEACAMs (namely, CEACAM1, CEACAM5, CEACAM6 and CEACAM7) have been found in epithelia. Theses CEACAMs members can mediate several cell signaling pathways and lead to various functions, such as tumor suppression/promotion, angiogenesis, lymphocyte activation, cell cycle and adhesion.