Claudin 18.2 Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (S-102-24),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	Claudin 18.2
Synonyms	CLDN18.2
Immunogen	Synthetic Peptide
Location	Cytoplasm, Cell membrane
Accession	P56856-2
Clone Number	S-102-24
Antibody Type	Recombinant mAb
Isotype	IgG
Application	IF
Reactivity	Hu, Ms, Rt
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Alexa Fluor® 647
Physical Appearance	Liquid
Storage Buffer	PBS, 0.1% BSA, 0.01% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
IF	1:200	null

Background

Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. Claudin 18.2 is involved in tumor development and progression and located in the outer cell membrane. It has exposed extracellular loops and is available for monoclonal antibody binding.