NA/LE Syrian Hamster anti-mouse CD28 mAb,specification,price,image-Bio-Equip in China

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Product Specification

Host	Syrian Hamster
Antigen	CD28
Immunogen	C57BL/6 mouse T cell lymphoma EL-4 cells
Clone Number	37.51
Antibody Type	Syrian hamster mAb
Isotype	Syrian Hamster IgG2
Application	in vitro T cell stimulation/activation, in vivo CD28 blockade
Reactivity	Ms
Purification	Protein G
Concentration	Lot specific* (generally 4 to 11 mg/ml)*
Molecular Weight	150 kDa
Purity	>95%(Determined by SDS-PAGE)
Endotoxin	<2EU/mg (<0.002EU/μg), 0.2 μM filtered Determined by LAL gel clotting assay
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH6.0 containing no preservative
Stability & Storage	2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

Background

This antibody recognizes the same epitope as clone 37.51.

This monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the lg superfamily, CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 augments lL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells. This antibody has been shown to stimulate the proliferation and cytokine production by activated T and NK cells and provide a costimulatory signal for CTL induction.