Human IgG1 F(c) Recombinant Rabbit mAb (S-447-20),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	Human IgG1 F(c)
Synonyms	Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1
Immunogen	Synthetic Peptide
Location	Secreted
Accession	P01857
Clone Number	S-447-20
Antibody Type	Recombinant mAb
Application	ELISA, WB, IHC-P, IF
Reactivity	Hu
Purification	Protein A
Concentration	0.25 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:500-1:10000
IHC	1:1000
IF	1:1000

Background

The intact antibody of human immunoglobulin (IgG) is composed of the fragment for antigen binding (Fab) and the crystallizable fragment (Fc) for binding of Fcγ receptors. Among the four subclasses of human IgG (IgG1, IgG2, IgG3, IgG4), which differ in their constant regions, particularly in their hinges and CH2 domains, IgG1 has the highest FcγR-binding affinity, followed by IgG3, IgG2, and IgG4 [PMID: 32370812].