CD8α Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (SDT-142-52),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Rabbit
Antigen	CD8α
Synonyms	Lyt-2
Immunogen	Synthetic Peptide
Location	Cell membrane
Accession	P01731
Clone Number	SDT-142-52
Antibody Type	Recombinant mAb
Application	FCM, IF
Reactivity	Ms
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Alexa Fluor® 647
Physical Appearance	Liquid
Storage Buffer	PBS, 0.1% BSA, 0.01% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
IF	1:200
FCM	1:200

Background

CD8α encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.