PCNA Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (SDT-297-116),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	PCNA
Synonyms	Proliferating cell nuclear antigen; Cyclin
Immunogen	Synthetic Peptide
Location	Nucleus
Accession	P12004
Clone Number	SDT-297-116
Antibody Type	Recombinant mAb
Isotype	IgG
Application	ICC, ICFCM
Reactivity	Hu, Ms, Rt
Positive Sample	HeLa
Predicted Reactivity	Av, Bv, Hm
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Alexa Fluor® 647
Physical Appearance	Liquid
Storage Buffer	PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
ICC	1:200	Hu
ICFCM	1:800	Hu

Background

Proliferating cell nuclear antigen (PCNA) is a type of DNA clamp that acts as a DNA polymerase in eukaryotic cells δ. The processing factor of is crucial for replication. PCNA is a homologous trimer that achieves its processability by surrounding DNA, where it serves as a scaffold for recruiting proteins involved in DNA replication, DNA repair, chromatin remodeling, and epigenetics. It is expressed in most tumors as a proliferative antigen.