RNA polymerase II CTD repeat YSPTSPS (phospho S2) Recombinant Rat mAb (S-R199),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rat
Antigen	RNA polymerase II CTD repeat YSPTSPS (phospho S2)
Synonyms	DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1; POLR2A
Location	Cytoplasm, Nucleus
Accession	P24928
Clone Number	S-R199
Antibody Type	Recombinant mAb
Isotype	IgG1
Application	WB, IHC-P, ICC, IF
Reactivity	Hu, Ms, Rt
Purification	Protein G
Concentration	0.4 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IHC	1:400
ICC	1:100
IF	1:100

Background

RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. The purified enzyme has typically 10–12 subunits (12 in humans and yeast). The subunit RPB1 contains a carboxy terminal domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity.