p21 Waf1/Cip1 Mouse mAb (469-2),specification,price,image-Bio-Equip in China

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Product Specification

Host	Mouse
Antigen	p21 Waf1/Cip1
Synonyms	WAFT, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, MDA-6, p21, CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1
Immunogen	Synthetic Peptide
Location	Nucleus
Accession	P38936
Clone Number	469-2
Antibody Type	Mouse mAb
Isotype	IgG2a
Application	WB, IHC-P, ICC, ICFCM
Reactivity	Hu
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IHC	1:500
ICC	1:500
ICFCM	1:50

Background

p21Cip1 (alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable of inhibiting all cyclin/CDK complexes [PMID: 8259214], though is primarily associated with inhibition of CDK2 [PMID: 8259214, PMID: 8242751]. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest [PMID: 9822382]. his protein is encoded by the CDKN1A gene located on chromosome 6 (6p21.2) in humans.