CD14 Mouse mAb (SDT-411-1),specification,price,image-Bio-Equip in China

Product Detail
Company Profile

Product Specification

Host	Mouse
Antigen	CD14
Synonyms	Myeloid cell-specific leucine-rich glycoprotein, Monocyte differentiation antigen CD14, FMC32lipopolysaccharide (LPS)
Immunogen	Synthetic Peptide
Location	Secreted, Golgi Apparatus, Cell membrane
Accession	P08571
Clone Number	SDT-411-1
Antibody Type	Mouse mAb
Isotype	IgG2a,k
Application	IHC-P, IF
Reactivity	Hu
Predicted Reactivity	C.el
Purification	Protein G
Concentration	1 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:1000
IF	1:500

Background

CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. It helps to detect bacteria in the body by binding lipopolysaccharide (LPS), a pathogen-associated molecular pattern (PAMP). CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol (GPI) tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa).